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Netochka Nezvanova
Highlights:
Netochka Nezvanova – a ‘Nameless Nobody’ – tells the story of a childhood dominated by her stepfather, Efimov, a failed musician who believes he is a neglected genius. The young girl is strangely drawn to this drunken ruin of a man, who exploits her and drives the family to poverty. But when she is rescued by an aristocratic family, the abuse against Netochka’s delicate psyche continues in a more subtle way, condemning her to remain an outsider – a solitary spectator of a glittering society. Conceived as part of a novel on a grand scale, Netochka Nezvanova remained incomplete after Dostoyevsky was exiled to Siberia for ‘revolutionary activities’ in 1849. With its depiction of the suffering, loneliness, madness and sin that affect both rich and poor in St Petersburg, it contains the great themes that were to dominate his later novels.
Never Let Me Go
Highlights:
In one of the most memorable novels of recent years, Kazuo Ishiguro imagines the lives of a group of students growing up in a darkly skewered version of contemporary England. Narrated by Kathy, now 31, Never Let Me Go hauntingly dramatises her attempts to come to terms with her childhood at the seemingly idyllic Hailsham School, and with the fate that has always awaited her and her closest friends in the wider world. A story of love, friendship and memory, Never Let Me Go is charged throughout with a sense of the fragility of life.If you enjoyed Never Let Me Go, you might also like Ishiguro’s The Remains of the Day, now available in Faber Modern Classics.
New Drug Development for Known and Emerging Viruses
Highlights:
Discusses how to fight Ebola, SARS Corona, and other known or emerging human viruses by building on the successes in antiviral therapy of the past decades Written by leading medicinal chemists from academia and industry, this book discusses the entire field of antiviral drug discovery and development from a medicinal chemistry perspective, focusing on antiviral drugs, targets, and viral disease mechanisms. It provides an outlook on emerging pathogens such as Ebola, Zika, West Nile, Lassa, and includes a chapter on SARS Coronoavirus-2 causing the present pandemic. New Drug Development for Known and Emerging Viruses describes the discovery and development process for antiviral agents for different classes of viruses and targets based on the experiences from the nine human viruses for which approved drugs are on the market (HIV, HCV, Influenza, RSV, HBV, HPV, HCMV, HSV, and VZV). It covers the properties and potential of 20 classes of currently approved antivirals, including combination drugs, and looks at novel antiviral strategies against emerging viruses. Covers the entire field of antiviral drug discovery and development Addresses the need for antiviral drugs to combat major health threats such as Ebola, Zika, West Nile, and SARS Coronavirus-2 Summarizes the successes of the past 15 years in developing ground-breaking medicines against 9 major human viruses, both from the medicinal chemistry and the pharmacological angle Discusses practical and strategic challenges in the drug discovery and development process, including screening technologies, latency, and toxicity issues New Developments in Antiviral Drugs is an important book for medicinal chemists, pharmaceutical chemists, virologists, and epidemiologists, and will be of great interest to those in the pharmaceutical industry and public health agencies.