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Computational Pharmaceutics
Highlights:
Molecular modeling techniques have been widely used in drug discovery fields for rational drug design and compound screening. Now these techniques are used to model or mimic the behavior of molecules, and help us study formulation at the molecular level. Computational pharmaceutics enables us to understand the mechanism of drug delivery, and to develop new drug delivery systems. The book discusses the modeling of different drug delivery systems, including cyclodextrins, solid dispersions, polymorphism prediction, dendrimer-based delivery systems, surfactant-based micelle, polymeric drug delivery systems, liposome, protein/peptide formulations, non-viral gene delivery systems, drug-protein binding, silica nanoparticles, carbon nanotube-based drug delivery systems, diamond nanoparticles and layered double hydroxides (LDHs) drug delivery systems. Although there are a number of existing books about rational drug design with molecular modeling techniques, these techniques still look mysterious and daunting for pharmaceutical scientists. This book fills the gap between pharmaceutics and molecular modeling, and presents a systematic and overall introduction to computational pharmaceutics. It covers all introductory, advanced and specialist levels. It provides a totally different perspective to pharmaceutical scientists, and will greatly facilitate the development of pharmaceutics. It also helps computational chemists to look for the important questions in the drug delivery field. This book is included in the Advances in Pharmaceutical Technology book series.
Comrades: Communism: A World History
Highlights:
Many years have passed since the collapse of communism in Eastern Europe and the USSR. Written by a historian of modern Russia, this book sets out to examine the history of communism throughout the world. It shows that although communism in its original form is dead or dying, the poverty and injustice that enabled its rise are dangerously alive.
Concerning Violence
Highlights:
Throughout history, some books have changed the world. They have transformed the way we see ourselves – and each other. They have inspired debate, dissent, war and revolution. They have enlightened, outraged, provoked and comforted. They have enriched lives – and destroyed them. Now Penguin brings you the works of the great thinkers, pioneers, radicals and visionaries whose ideas shook civilization and helped make us who we are.
Angered by the racism he witnessed on Martinique during the Second World War, Fanon here examines the roles of class, culture and violence, and expresses his profound alienation from the idea of colonialism and its bloodshed. More than four decades on, Fanon’s work still inspires liberation movements today.
Concerning Violence
Highlights:
Throughout history, some books have changed the world. They have transformed the way we see ourselves – and each other. They have inspired debate, dissent, war and revolution. They have enlightened, outraged, provoked and comforted. They have enriched lives – and destroyed them. Now Penguin brings you the works of the great thinkers, pioneers, radicals and visionaries whose ideas shook civilization and helped make us who we are.
Angered by the racism he witnessed on Martinique during the Second World War, Fanon here examines the roles of class, culture and violence, and expresses his profound alienation from the idea of colonialism and its bloodshed. More than four decades on, Fanon’s work still inspires liberation movements today.
Confessions of an Economic Hit Man
Highlights:
As an EHM in the ’60s and ’70s, covertly recruited by the US National Security Agency, John Perkins helped further American imperial interests in countries such as Ecuador, Panama, Indonesia and Saudi Arabia. He tried to write this book four times but was threatened or bribed each time to halt. The events of 9/11 – a direct result of the activities of EHMs in the 1970s – finally forced him to confront the role he played himself, and to reveal the truth to the rest of the world. “Confessions of an Economic Hit Man” has become a word-of-mouth bestseller in the US. It has been called the book that finally ‘connects the dots, the book that best explains what is really going on in the world’. Once you’ve read it you will find yourself recommending it to everyone you know. It can truly change the way you view the world. As one US reader writes: ‘I feel that this is not just a book – it is an event, with powerful cultural and political ramifications. This book turns our understanding of history upside down, and I implore you to read it as soon as you possibly can. The more people who are aware, the more easily change can brought about.’ Following his EHM work, Perkins founded Independent Power Systems, an alternative energy provider that successfully changed the US utility industry. He is now president of Dream Change Coalition, a nonprofit organization working with Amazonian and other indigenous people to help preserve their environments and cultures. ‘As I travel around the world, I find that people know that their country just received a billion-dollar loan, for example, from the World Bank and that American corporations are there benefiting from the loan, but that their own lives are getting worse,’ he says.